Gavrilov, L.A., Gavrilova, N.S. What Can We Learn about Aging and COVID-19 by Studying Mortality?. Biochemistry Moscow 85, 1499–1504 (2020). https: ...

Текст статьи на сайте журнала URL: https://link.springer.com/article/10.1134%2FS0006297920120032 (дата обращения 14.01.2021)

Abstract

Promising ideas and directions for further research into biology of aging are discussed using analysis of the agerelated kinetics of organisms’ mortality. It is shown that the traditional evolutionary theory explaining aging by decreasingforce of natural selection with age is not consistent with the data on agerelated mortality kinetics. The hypothesis of multistage destruction of organisms with age, including the ratelimiting stage of transition to a state of nonspecific vulnerability (“nonsurvivor”), is discussed. It is found that the effect of the COVID19 coronavirus infection on mortality is notadditive (as it was the case with the Spanish flu epidemic in 1918), but multiplicative (proportional) for ages over 65 years.

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